Ichiro Shima Selected Research

8- (4- fluorophenyl)- 2- (3- phenyl- 2- propenoyl)- 1,2,3,4- tetrahydropyrazolo(5,1- c)(1,2,4)triazine

12/2003

A novel potent radical scavenger, 8-(4-fluorophenyl)-2-((2E)-3-phenyl-2-propenoyl)-1,2,3,4-tetrahydropyrazolo[5,1-c] [1,2,4]triazine (FR210575), prevents neuronal cell death in cultured primary neurons and attenuates brain injury after focal ischemia in rats.

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Ichiro Shima Research Topics

Disease

1	Ascites 12/2012
1	Lymph Node Tuberculosis (Scrofula) 12/2012
1	Tuberculous Peritonitis 12/2012
1	Lymphadenopathy 12/2012
1	Tuberculosis (Tuberculoses) 12/2012
1	Hypotension (Low Blood Pressure) 09/2008
1	Peritonitis 09/2008
1	Type 2 Diabetes Mellitus (MODY) 08/2008
1	Abdominal Pain (Pain, Abdominal) 06/2004
1	Intussusception 06/2004
1	Ischemia 12/2003
1	Brain Injuries (Brain Injury) 12/2003
1	Brain Ischemia (Cerebral Ischemia) 12/2003
1	Reperfusion Injury 12/2003
1	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2003
1	Stroke (Strokes) 12/2003

Drug/Important Bio-Agent (IBA)

1	Adenosine DeaminaseIBA 12/2012
1	A-Form DNA (A-DNA)IBA 12/2012
1	Antitubercular AgentsIBA 12/2012
1	AlbuminsIBA 09/2008
1	Hypoglycemic Agents (Hypoglycemics)IBA 08/2008
1	Dipeptidyl-Peptidase IV InhibitorsIBA 08/2008
1	8- (4- fluorophenyl)- 2- (3- phenyl- 2- propenoyl)- 1,2,3,4- tetrahydropyrazolo(5,1- c)(1,2,4)triazineIBA 12/2003
1	TriazinesIBA 12/2003
1	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2003
1	Neuroprotective AgentsIBA 12/2003

Therapy/Procedure

1	Drug Therapy (Chemotherapy) 12/2012
1	Renal Dialysis (Hemodialysis) 06/2004
1	Therapeutics 06/2004
1	Intravenous Infusions 12/2003